Purpose
Sequencing projects can lock onto a platform or panel before target breadth, sensitivity, enrichment, workflow, and validation consequences are made explicit.
science software · 2026
NGS Assay Planner
A vendor-neutral planning tool for comparing plausible NGS assay strategies before detailed design begins.
My role
Product designer, domain expert, and engineer
Status
prototype
Methods
- TypeScript
- Deterministic rules
- Typed planning models
- Validation-aware reporting
- Scientific UX
Outputs
- Interactive planning report
- Strategy comparison
- Risk and validation checklist
Result
A working browser prototype that makes assay-planning assumptions and tradeoffs inspectable.
Implementation
How it works
A deterministic TypeScript rules engine compares amplicon, hybrid capture, exome, whole-genome, and metagenomic strategies using stated requirements, tradeoffs, risk flags, and validation considerations.
The browser build mirrors a Python reference implementation and uses static example scenarios, cost tiers, and vendor examples. It remains planning-only and requires expert review.